There are many allergic dermatitis that cause skin to be particularly itchy at night, such as eczema, urticaria, etc. It is recommended to take general treatment, medication and other ways to improve. 1. Eczema: eczema will appear intense itching symptoms, will be paroxysmal aggravation, night symptoms will be exacerbated, resulting in the skin particularly itchy at night, the patient should identify the causative agent, and avoid scratching the affected area. It is recommended that patients follow the doctor’s instructions to apply glucocorticoid drugs, such as dexamethasone, dianabed, etc., can help stop itching, anti-inflammatory, anti-allergic. 2. Urticaria: Urticaria will be all day or intermittent attacks, may trigger the skin at night especially itchy, patients should avoid contact with triggers of the disease, you can follow the doctor’s instructions to take oral antihistamines, beneficial to stop itching, anti-allergy, common drugs, including cetirizine, loratadine and so on. For patients suffering from atopic dermatitis, resulting in the skin particularly itchy at night, it is recommended to consult a doctor for examination, to clarify the cause of the disease, and cooperate with the doctor for standardized treatment.