Blood in stool with blood clots and mucus may be related to inflammatory bowel disease, intestinal infectious diseases, intestinal tumors and other reasons. 1. Inflammatory bowel disease: such as ulcerative colitis, Crohn’s disease, due to the mucosa of the intestinal tract occurs in the erosion of ulcers, there may be blood in the stool with blood clots and mucus. 2. Intestinal infectious diseases: such as bacteria and other pathogens infected with intestinal tract, such as acute enteritis, dysentery, etc., may appear mucosal inflammatory manifestations, there may be blood in the stool with blood clots and mucus. 3. Intestinal tumors: such as colorectal adenocarcinoma, rectal cancer, etc. can cause erosion and necrosis of the intestinal mucosa, which may lead to the appearance of mucus blood in stool. It is suggested that those who have blood in stool with blood clots and mucus should go to the hospital in time, have a systematic examination to clarify the cause of the disease, and have standardized treatment under the guidance of professional doctors, so as to avoid delaying the condition.