What to do exactly for cough, sore throat and phlegm cannot be generalized and should be treated according to the different causes of cough, sore throat and phlegm, which can be caused by pathogenic microbial infections such as bacteria, viruses, mycoplasma and chlamydia. If it is caused by a viral infection, antiviral treatment can be given. If it is caused by bacterial infection, antibiotic anti-infection treatment can be given, commonly used are amoxicillin of penicillin, cephalosporin of cefadroxil, cefaclor, azithromycin of macrolide, etc. In the case of adults over 18 years of age, anti-infective treatment with antibiotics of the quinolone class, such as levofloxacin mesylate, is also available. If the infection is caused by atypical pathogens, such as mycoplasma, chlamydia, etc., anti-infective treatment can be performed with macrolides or quinolones, and it should be noted that quinolone antibiotics should be used for adults over 18 years of age. For example, coughing, yellow mucous sputum, and sore throat belong to wind-heat or phlegm-heat type. If the cough is caused by wind-heat or phlegm-heat, we can use Yin Qiao San plus or minus, and if the cough is caused by phlegm-heat, we can use Qing Jin Hua Phlegm Tang plus or minus. If the cough, little or no phlegm, with a little blood in the phlegm, accompanied by irritable heat in the five hearts, hot flashes and night sweats, and redness in the cheekbones, belongs to the type of cough, sore throat and phlegm with yin deficiency and lung dryness, it can be treated with Sha Shen Mai Dong Tang to nourish yin and moisten the lung and stop cough and resolve phlegm.