The risks of minimally invasive brain surgery are very high and must be treated specifically according to the specific shape of the situation. After all, the brain is the command center of the human body, and once this area is damaged, regardless of any small aspect, it may cause adverse consequences. It is important to pay attention to the idea that the risks of surgery are very high. Minimally invasive surgery includes many types of procedures, including transnasal pterygoid approach to remove pituitary tumors, stenting, spring coil embolization, and a variety of other minimally invasive surgical treatments. It is important to be clear about the type of minimally invasive surgical procedure to better evaluate the risk of surgery. Generally speaking, the risk of minimally invasive surgical treatment is much greater for hemorrhagic disease than for ischemic disease. Early clarification of the changes in one’s condition and the type of minimally invasive surgery to be performed is necessary for the clinical prognosis of the patient.