Ulcers of the terminal ileum may be common ulcers. The so-called common ulcers are benign lesions not malignant tumors, mainly associated with the local mucosal inflammatory reaction, the clinical causes of the corresponding conditions mainly include infection, tuberculosis and immune system diseases. 1. Infection: bacterial growth at the end of ileum may lead to local intestinal inflammation and cause common ulcer. 2. Tuberculosis: Mycobacterium tuberculosis, which enters the intestines through the digestive system, eventually accumulates at the end of the ileum and may cause tuberculosis infection in the corresponding area, resulting in the production of localized ulcers. 3. Immune system diseases: the most common is Crohn’s disease and ulcerative colitis, resulting in localized metabolic inflammation, can also cause the corresponding parts of the ulcer. Ulcers at the end of the ileum, need to take out a part of the tissue to do pathology, combined with the results of pathological examination for comprehensive judgment, under the guidance of the clinician for standardized treatment, so as not to delay the condition.