Non-gonococcal urethritis is judged to be cured and recovered when it turns negative, and when the pathogen test is negative and the symptoms disappear. Most of the non-gonococcal urethritis is caused by Chlamydia trachomatis, Mycoplasma genitalium, Mycoplasma urealyticum and other pathogenic bacteria infection of the genitourinary tract urinary infection. According to the drug sensitivity test to choose sensitive antibiotics, active standardized treatment, the treatment effect is basically very good. Determine the time schedule of the cure test: antigen detection test for 2 weeks after the end of the course of treatment, nucleic acid amplification test for 4 weeks after the end of the course of treatment. The pathogen test turns negative, the symptoms disappear, can be judged as cure recovery. Non-gonococcal urethritis should be treated in accordance with the doctor’s instructions, regular review, and both husband and wife at the same time, so as not to cause cross-infection again.