The difference between raw and ripe ground is mainly manifested in the concoction, flavor and attribution, efficacy and main treatment. 1. Concoctions: Raw ground is the fresh or dried tuberous roots of the genus Dioscorea of the family Xuanzhenshenidae; ripened ground is the tuberous roots of Dioscorea, processed and steamed and sun-dried, and the traditional concoctions with better medicinal effects need to be made after nine steamed and nine sun-dried. 2. Flavor and Meridian: Shengdi, sweet, bitter, cold, into the heart, liver, kidney meridian; ripe ground, sweet, slightly warm, to the liver, kidney meridian. 3. Efficacy and Indications: Radix et Rhizoma Shengdi has the effects of clearing heat and cooling the blood (relieving blood heat by clearing heat), and nourishing yin and generating fluids (nourishing yin fluid to generate fluids). It is mainly used for treating internal heat due to yin deficiency (fever caused by deficiency of yin fluid), internal heat and thirst (internal heat accompanied by symptoms such as excessive eating, drinking and urination), and intestinal dryness and constipation (constipation due to deficiency and dryness of intestinal fluid). Radix Rehmanniae Praeparata has the effects of nourishing Yin and replenishing Blood (nourishing the blood in the body), benefiting the essence and filling the marrow (replenishing the kidney essence to fill up the bone marrow), and is mainly used in treating Blood deficiency with yellowish color (yellowish coloring of the skin due to deficiency of blood), Kidney-Yin insufficiency (deficiency of Yin in the kidneys), soreness of the waist and knees (a feeling of soreness and weakness in the waist and knees), spermatorrhea, dizziness, vertigo, and premature graying of the beard and hair. If there is a need for medication, a Chinese medicine practitioner should be consulted for evidence-based guidance and medication should be administered according to the doctor’s prescription.