Sepsis often leads to systemic multiple organ function involvement, and its complications are varied: 1, respiratory failure: the emergence of dyspnea, shortness of breath, cyanosis of the lips and mouth, transcutaneous oxygen drop and hypoxia, do tracheal intubation and ventilator therapy to maintain the patient’s lung function; 2, circulatory failure: including cardiac insufficiency and a variety of arrhythmia, can be accompanied by cardiac enzyme spectrum elevation. If the blood pressure still cannot be corrected by volume compliance, consider septic shock.3. Renal dysfunction: elevated creatinine, oliguria or acidosis, electrolyte disorders, use diuretics or do bedside hemodialysis treatment to maintain renal function;4. Impaired cerebral function: impaired consciousness, epilepsy, or delirium, also known as sepsis-associated encephalopathy;5. Hematologic system: abnormal coagulation indexes, systemic hemorrhagic spots.6. Digestive system : Abdominal pain, abdominal distension, abdominal hypertension and abdominal septal compartment syndrome. Gastrointestinal bleeding. Jaundice. There are also endocrine and other systems that are affected by sepsis and produce complications.