Taking statins after drinking alcohol will affect the function of the liver and may lead to liver failure in severe cases. Statin is a cholesterol-lowering drug, the vast majority of statins are metabolized through the liver, the main mechanism of action is to inhibit cholesterol synthesis in the liver so as to play a lipid-lowering effect, but long-term use can cause liver toxicity and muscle toxicity and other side effects, the patient will be elevated transaminases, so patients taking statins should be regularly tested liver function. Alcohol is also metabolized by the liver, and drinking alcohol will inevitably cause problems with the metabolism of statins, and it is possible that taking a statin after drinking alcohol will increase the risk of liver injury. And long-term large amount of alcohol intake will also lead to fatty liver, alcoholic liver and even cirrhosis and other liver problems. Therefore, it is not recommended to take statin after drinking alcohol to avoid adverse consequences.