A glycated hemoglobin of 12.5% is more serious. Glycosylated hemoglobin is the product of combining hemoglobin from red blood cells with sugars in the serum, and can help diagnose diabetes, reflecting blood glucose control over the last 3 months. The normal value of glycated hemoglobin is 4% to 6%. Glycated hemoglobin 12.5% is far beyond the normal range, so glycated hemoglobin 12.5% is more serious. Glycated hemoglobin 12.5% indicates that the patient’s blood glucose concentration is high, the main causes of the disease are diabetes and hyperglycemia, the main treatment is life guidance and medication, oral hypoglycemic drugs under the guidance of the doctor, such as metformin, etc., but also insulin therapy, insulin therapy should be strictly in accordance with the doctor’s instructions to avoid the emergence of blood glucose is too low and other situations. It is recommended that patients with abnormal glycosylated hemoglobin should consult a doctor in time and standardize the treatment under the guidance of the doctor to avoid delaying the condition.