Patient: December 2009. Leukocytosis, thrombocytosis. A doctor in Jingzhou, Hubei. I’ve been taking hydroxyurea and a Chinese medicine whose name I don’t know, which is said to be very effective for this disease. Even can be cured of a Chinese medicine. Yesterday I just went to the hospital to check the blood, white blood cells have dropped to 16.31. The platelets have returned to normal. 4.5 months ago my white blood cells also returned to normal once, and then I reduced the amount of hydroxyurea. But it didn’t take long for the white blood cells to grow back. I have been taking hydroxyurea at the same dosage until now. Two times a day. Two pills at a time. The doctor checked my chromosomes and they were negative. Can I be cured by taking only hydroxyurea and herbs without taking Gleevec or transplant? Do I have to have a transplant to get better? I read some reports that. The disease can be stable for 1 to 4 years, and then enters an accelerated phase with rapid onset of anemia and more symptoms. After that, the disease turns into acute myeloid leukemia. Is this true? Cui Guohui, Department of Hematology, Wuhan Union Medical College Hospital
The results of the bcr/abl fusion gene test? For typical chronic granulocytosis (Ph chromosome positive), if only hydroxyurea treatment is applied, it can only improve the symptoms, not cure, and the disease will enter the accelerated phase and finally become acute in about 3 years on average. If the disease is negative at the time of diagnosis, it is atypical lentile, a condition that cannot be treated with Gleevec, but only by transplantation.