It is not recommended to take the quadruple pill for 7 days, and the quadruple therapy regimen lasts 10 to 14 days. Quadruple therapy is a regimen developed to eradicate H. pylori and includes a proton pump inhibitor, a bismuth agent, and two antibiotics. Commonly used proton pump inhibitors include omeprazole, lansoprazole, pantoprazole, rabeprazole, etc., bismuth agents include bismuth potassium citrate, bismuth pectin, etc., and antibiotics commonly used are amoxicillin, clindamycin, metronidazole, tinidazole, etc. Quadruple therapy, if administered for 7 days, has a low eradication rate of H. pylori and is likely to lead to recurrence. It is standard to use the medication for 10 to 14 days, and stop the medication for one month after 14 days, and repeat the urea breath test to determine the eradication of H. pylori. All of the above medications should be used under a doctor’s supervision, avoid self-medication.