Uremia belongs to the advanced stage of chronic renal failure and is generally incurable. At present, the main clinical treatments are drug conservative treatment and renal replacement therapy. Drug therapy can be used when the blood creatinine control is more stable, not combined with severe acidosis, hyperkalemia, high degree of edema, oliguria. To correct metabolic acidosis, oral sodium bicarbonate can be used; to control water and sodium disorders, diuretics such as furosemide and torasemide can be used; detoxification drugs can be chosen such as renal failure capsules. Renal replacement therapy includes hemodialysis, peritoneal dialysis, and kidney transplantation. Patients with uremia can choose renal replacement therapy as their kidney function is severely damaged and their kidney function is almost completely lost, and the effect of drug treatment is poor. If hemodialysis or peritoneal dialysis treatment is carried out, generally speaking, it needs to be carried out regularly for a long period of time. Once the replacement therapy is interrupted, the toxin substances will accumulate rapidly in the patient’s body, and the patient’s condition will deteriorate rapidly in a short period of time. Kidney transplantation is to transplant a healthy kidney to a patient with loss of kidney function, and long-term oral medication is needed to inhibit the rejection reaction after the operation. Patients with uremia need to consult regular hospitals, and the choice of treatment should be based on the severity of the disease and the doctor’s advice.