In the absence of exercise, the thigh muscles appear sore and painful generally speaking, the common causes are mainly the following conditions. First, deep vein thrombosis of the lower limbs, resulting in obstruction of venous blood return at the thigh, more blood pooling in the lower limbs, and causing local swelling and soreness symptoms. At this time, the patient can inject low molecular heparin subcutaneously, apply dextran and hemosiderin intravenously, and take aspirin orally to promote the dissolution and absorption of venous thrombus faster, so as to relieve the soreness and pain of thigh muscles. Secondly, patients with severe varicose veins in lower limbs have a large amount of lactic acid and metabolic waste accumulation due to the superficial tortuous blood vessels. This can cause soreness in the thigh muscles of the patient, and at this time the patient can have the trunk of the varicose vessels completely stripped by surgery and the branches carefully ligated. Postoperative compression bandages are applied to completely stop the bleeding, thus reducing the symptoms of soreness in the thigh muscles.