Numbness in the wrist of both hands is commonly caused by peripheral nerve injury, and can be accompanied by numbness in the distal part of both lower limbs, at this time, it is recommended to check the peripheral nerve conduction velocity, to see if there is any damage to the peripheral nerves. Common causes are diabetes, long-term alcohol consumption, resulting in peripheral nerve damage. Numbness of both wrists can also be seen in cerebrovascular diseases, such as ischemic cerebrovascular disease, that is, caused by cerebral infarction, but also in cervical spine diseases, such as cervical disc herniation compression of the nerve root caused by the numbness. For different cases, it is necessary to improve the relevant auxiliary examination, such as checking the MRI of the cervical spine and cranial imaging examination. For peripheral nerve injury, you can also take B vitamins for treatment, such as vitamin B12, vitamin B1, vitamin B6 and so on. Further exceptions should be made for diseases such as carpal tunnel syndrome.