If you wake up at night and can’t sleep, if it occurs occasionally, it may be caused by mental stress and excessive tension during the day, you can exercise or count, drink a glass of hot milk and listen to moderate music may improve. If it occurs frequently, it may be caused by certain diseases, such as depression, and the patient may have psychological symptoms, including depressed mood, reduced self-esteem, and disinterest in everything. Some patients show self-guilt and self-blame, believing themselves to be incompetent. Patients may have the desire to live lightly in severe cases, mainly with antidepressant treatment, applying citalopram, but also mirtazapine and Dexedrine, etc. If the patient has neurasthenia may also appear, the main is to regulate the plant nerve treatment, can apply glutathione and tranquilizer, in severe cases can apply a small dose of sedative drugs. Menopausal patients can also appear, mainly caused by endocrine dysfunction, the patient is instructed to exercise properly, appropriate participation in outdoor sports, may improve the symptoms, if necessary, the application of small doses of sedative drugs or glutamate, etc..