Nephrectomy is mainly done by laparoscopic surgery, which is usually not painful during the operation. Nephrectomy surgery is usually done laparoscopically to complete the nephrectomy operation, which needs to be carried out under general anesthesia. Therefore, during laparoscopic nephrectomy surgery, the patient will not feel any pain at all due to the implementation of general anesthesia and loss of consciousness. However, as the anesthesia wears off after the operation, the surgical wound may experience slight pain. A few patients are more sensitive to pain and will feel obvious pain after the operation, they can take pain relieving drugs such as tramadol and diclofenac sodium under the guidance of professional doctors. If you have a malignant tumor of the kidney, in view of the seriousness of the condition and the need for nephrectomy, it is recommended to cooperate with the attending physician as soon as possible for surgical treatment, and there is absolutely no need to worry too much about the pain of the operation.