The difference between peritoneal perfusion chemotherapy and thermal perfusion chemotherapy is as follows: 1. Peritoneal perfusion chemotherapy is a new selective regional chemotherapy designed according to the anatomical and physiological characteristics of the abdominal cavity, and some studies have proved that the advantages shown by peritoneal drug administration are equivalent to those achieved only by intravenous drug administration several times. The efficiency of systemic chemotherapy for malignant peritoneal effusion is only 20%-30% because of the low concentration of drugs distributed to the peritoneal cavity through the blood circulation. The use of intraperitoneal perfusion chemotherapy can increase the local drug concentration to 10-100 times that of intravenous administration, and the drug contouring rate is only 1/10 of that in plasma, so it is conducive to killing tumor cells in the abdominal cavity, and its efficiency is significantly higher than that of systemic chemotherapy; 2. Thermal perfusion chemotherapy of the abdominal cavity is to heat the liquid containing chemotherapy drugs to a certain temperature and inject it into the abdominal cavity for circulating thermal perfusion or for external heating to maintain the temperature in the abdominal cavity for a longer period of time. The temperature in the abdominal cavity is kept constant for a long time to remove the free cancer cells in the abdominal cavity, kill the residual subclinical lesions therein, prevent recurrence after surgery and postoperative implantation and metastasis, increase the survival rate of patients and improve their prognosis. During the process of abdominal thermal perfusion chemotherapy, the peritoneum of the dirty wall layer and the vascular bed of each organ in the abdominal cavity can absorb a large amount of heat, which can cause the patient’s body temperature to rise and can achieve the purpose of systemic thermotherapy.