When using ibuprofen for fever reduction, the use of ibuprofen tablets is recommended only when the body temperature reaches 38.5°C or exceeds 38.5°C. If the fever persists, it is recommended to use it again at an interval of 4-6 hours, and it should be noted that it must not be used more than 4 times within 24 hours. If the symptoms are not relieved or worsen after 3 days of applying ibuprofen tablets to reduce fever, it is recommended to stop the drug and seek medical attention. Concurrent use of other non-steroidal anti-inflammatory and analgesic drugs such as naproxen, diclofenac sodium, acetaminophen, etc. is not recommended during the use of ibuprofen tablets. It is also not recommended to use at the same time compound preparations for the treatment of colds, such as 999 cold and flu granules, Sensac or Crypto. Because these drugs contain non-steroidal anti-inflammatory and analgesic drugs, that is, acetaminophen.