Cancer is a generic term for a large group of malignant tumors, and different parts of the cancer may be treated differently in the middle and late stages or in different ways. Generally, it is possible to be cured in the middle and late stages, but it is very difficult. Generally, there is still a chance of surgical cure in the middle stage, for example, in the middle stage of esophageal cancer or breast cancer, which can be combined with radiotherapy and chemotherapy after surgery. If there is no recurrence for more than 5 years, it is considered to be clinically cured and cured, but it is not certain that there will be no recurrence after 5 years, and it has to be reviewed at least once a year. For other advanced cancers, if there is extensive metastasis and there is no way to treat it surgically, palliative surgery or tumor reduction surgery can be considered, but it may not be very useful for prolonging survival. It is not completely curable, but only palliative radiotherapy can be done to control the development of the disease and prolong the survival.