Epidermolysis bullosa is a rare and genetically related skin disease. The skin of patients with epidermolysis bullosa is very fragile and can seriously affect the normal life of patients. In clinical practice, the following options are mainly used to treat epidermolysis bullosa: 1. Treatment with sebaceous steroid hormones, such as methylprednisolone tablets, prednisone acetate tablets, etc. Topical treatment with compound flumethasone ointment, or mometasone furoate cream. 2, antibiotic treatment, antibiotics can be used to prevent or control complications of epidermolysis bullosa infection, such as cefuroxime tablets, azithromycin tablets, etc. 3, vitamin tablets and sodium citrate adjuvant treatment, if patients with other systemic lesions need symptomatic treatment. 4, Chinese herbal medicine treatment, the main choice of spleen strengthening and dampness removal herbal Herbs, boiled into a soup for a long time to take, such as honeysuckle, white peony, etc.