There are many types of antihypertensive drugs for patients with uremia, including beta-blockers, angiotensin-converting enzyme inhibitors, angiotensin II receptor antagonists, calcium antagonists, etc. However, for each patient with uremia, the choice of antihypertensive drugs should be based on the patient’s specific situation. However, for each patient with uremia, the choice of antihypertensive drugs should also be combined with the patient’s specific situation, such as patients with significant bradycardia, or the presence of significant second-degree or third-degree atrioventricular block, in the choice of antihypertensive drugs, should be avoided as much as possible the application of β-blocker drugs, so as not to lead to the patient’s heart rate progressive decline, and even the emergence of cardiovascular adverse events. For uremic patients, in addition to the choice of antihypertensive drugs to control blood pressure, should be from the rhythm of life, dietary structure adjustment and other aspects of the reasonable promotion of blood pressure decline, for example, as far as possible to control sodium intake, to ensure that the patient’s fluid in and out of the balance of the amount of patients, etc., are helpful to the patient’s blood pressure decline.