Peeling hands during seasonal change can be relieved by topical moisturizers, medications, or a combination of internal medications. Peeling hands during the change of season is a common symptom, mostly caused by dry skin on the palms of the hands, lack of vitamins, or allergic factors. Early hand peeling symptoms can be soaked in warm water every day for 10-15 minutes, the dry skin soak soft, and then use petroleum jelly or glycerin coated, you can also use vitamin E cream, Vitamin A acid ointment coated can be effective in relieving the symptoms, if the peeling of the skin is serious can be combined with oral medication, such as multivitamin tablets, Vitamin AD pills, etc., you can receive very good results. In addition, for some allergic factors lead to hand peeling, often feel the hand itching, this situation need to apply some weak glucocorticoid ointment, such as fluoride acetate easy ointment, hydrocortisone butyrate cream, etc., can relieve the hand itching and peeling symptoms. Patients with peeling hands should have a light diet, balanced nutrition, and avoid contact with some alkaline substances to prevent the condition from worsening.