Early morning, when blood pressure control is at its worst in patients with hypertension, is also a risk time for heart disease, with about 40% of myocardial infarctions and 29% of sudden cardiac deaths occurring early in the morning and in the morning. So why is blood pressure higher in the morning? Under normal circumstances, human blood pressure is not constant throughout the day, but fluctuates within a certain range. There are “two peaks and a valley” of blood pressure. The two peaks occur in the early morning from 6:00 to 10:00 and in the afternoon from 4:00 to 6:00, with the first peak being more pronounced. The “valley” occurs between 2:00 am and 4:00 am. The low blood pressure during nighttime sleep and the significant increase in blood pressure in the early morning hours is called the “morning peak phenomenon”, which may be related to the body’s biological rhythm. At dawn, the autonomic nervous system and related humoral factors of the cardiovascular system enter a state of excitement and stress, prompting an increase in heart rate, blood pressure, and cardiac blood displacement. However, in patients with hypertension, this volatility can be even greater, and blood pressure may be outside the normal range by the time they wake up in the early morning. Therefore, it becomes more important to control blood pressure in the early morning. So, how can we reduce the occurrence of cardiovascular events during the “morning peak”? It is recommended that you sit in bed for a while after waking up before getting out of bed. Don’t worry too much about taking medication on an empty stomach to stimulate your stomach. In fact, taking medication on an empty stomach will promote the speed of emptying of the drug in the stomach, which in turn will work faster and have fewer side effects in the stomach. There are several other points to note: try to use long-acting antihypertensive drugs that are taken only once a day. Such a drug blood concentration is maintained for a longer period of time, which can effectively cover the morning time period and stabilize blood pressure. For those whose blood pressure is difficult to control at night and early morning, another dose can be taken in the late afternoon or before bedtime (this must be applied under the guidance of a doctor). Patients must have their blood pressure measured on time, and if they find that their blood pressure is poorly controlled they should seek immediate medical attention to adjust their medication in a timely manner.