During menstruation, the pain in the lower abdomen is more serious, mainly related to the following factors: first, due to individual differences, during menstruation, the endometrial shedding will secrete a large amount of prostaglandins. Prostaglandins will cause uterine smooth muscle contraction, which will lead to severe lower abdominal pain, and even cause nausea and vomiting symptoms. Second, it is caused by endometriosis. When endometriosis is menstruating, the foci of endometriosis will also bleed, if the foci of endometriosis is in the myometrium, then the myometrium will bleed, and if it is in the ovary, then the localization of the ovary will also bleed, so it will lead to very serious lower abdominal pain, and it is recommended to investigate the cause clinically, and then give the appropriate treatment.