The main symptoms of multiple sclerosis (MS) include limb weakness, sensory abnormalities, eye discomfort, ataxia, etc. Accompanying symptoms may also occur, and it is recommended that patients seek timely medical treatment. 1. Weakness of limbs: the most common symptom is weakness of one or more limbs, such as hemiplegia, paraplegia, quadriplegia, etc. The most common symptom is asymmetrical paralysis. 2. Sensory abnormalities: such as coldness, itching, ants, burning pain, and pins and needles numbness in the limbs, trunk or face. 3. Eye discomfort: mainly acute optic neuritis or retrobulbar optic neuritis, usually manifested as the onset of monocular vision loss, but also double vision, some patients may also appear diplopia, ocular muscle paralysis and other symptoms. 4. Ataxia: manifested as motor clumsiness, incoordination, unsteady gait, abnormal posture and so on. 5. Accompanying symptoms: such as urinary frequency, urinary urgency, urinary retention, urinary incontinence and other bladder dysfunctions, male patients may also have sexual dysfunction, some patients may also have depression, irritability, apathy, lethargy, unresponsiveness and other mental symptoms. Patients with the above symptoms, suspected the existence of multiple sclerosis, should promptly consult a doctor to improve the relevant examinations, such as cerebrospinal fluid examination, magnetic resonance imaging, electrophysiological examination, so as to clarify the diagnosis of the disease and carry out the appropriate treatment, do not blindly judge on their own, in order to avoid delaying the condition.