Transmission of syphilis can usually be prevented by transfusion of blood that has been preserved for more than 3-6 days. A chronic disease caused by the transmission of the syphilis spirochete is known as syphilis. Blood, semen and other body fluids contain the presence of the syphilis spirochete, and the source of transmission of syphilis is the person with syphilis, who may become infected with syphilis if he or she is fed blood from a person with syphilis. However, the syphilis spirochete is usually not easy to survive after leaving the body. The syphilis spirochete can survive for 48 hours at 0°C, while it usually loses its viability in about 3-6 days in the 4°C environment of refrigerated blood. Therefore, to avoid transmission of syphilis spirochetes, it is recommended to transfuse blood that has been stored for at least 3 days. It is also possible to transmit syphilis when there are tiny broken wounds in the skin and mucous membranes, if they inadvertently come into contact with the body fluids of a syphilitic patient. If a patient with syphilis is untreated, his body fluids are usually highly contagious within 1-2 years. Therefore, in addition to the blood transfusion should pay attention to prevent syphilis infection, life also need to avoid unclean sexual behavior, avoid sexual contact with syphilis patients, avoid sharing towels, washcloths and other items, in order to prevent syphilis infection.