There is a lack of specific treatment for burning mouth syndrome. Treatment consists of local and systemic medications, mainly antidepressants. 1. Systemic medication: clonazepam is the first-line drug for the treatment of burning mouth syndrome, tricyclic antidepressants, such as amitriptyline, and anticonvulsants, such as carbamazepine, can also be used as appropriate. The above drugs can cause drowsiness, mild headache, malaise, and dyskinesia, depending on the dose. Allergic people are prohibited, pregnant and lactating women are prohibited. 2. Topical medication: Studies have shown that clonazepam in topical form applied to the painful area can relieve the discomfort of burning mouth syndrome. If you suffer from burning mouth syndrome, it is recommended that you consult a doctor promptly. All of the above medications should be used under medical supervision.