The main manifestations of Parkinson’s disease

Parkinson’s syndrome is a common diagnostic concept used by neurologists in clinical practice. It refers to a group of clinical syndromes caused by various causes (cerebrovascular disease, cerebral atherosclerosis, infection, poisoning, trauma, drugs, and genetic degeneration, etc.), mainly manifesting as tremor, muscle rigidity, motor retardation, and postural instability. These include primary Parkinson’s disease, Parkinson’s superimposed syndrome, secondary Parkinson’s syndrome and genetic degenerative disease Parkinson’s syndrome. Parkinson’s disease usually starts insidiously and is not easily detected by the person himself or his family. The disease progresses relatively slowly and shows a gradual aggravation. It often starts with the fingers on one side and gradually expands to the leg on the same side and the opposite limb. The jaw, mouth, lips, tongue and head often have no or last symptoms. The tremors in Parkinson’s patients are characteristic: the thumb and flexed index finger show “pill rolling” or “bill counting” like movements, which can be repeated 4-6 times a second, often when the hand is placed on the thigh in a resting position or more obvious; when When attention is shifted and other movements are performed, it is reduced or stopped, and it is aggravated when nervousness is present and disappears after sleep. Patients are often unable to make fine movements, such as untying and tying shoelaces, buttoning, etc. 2, muscle stiffness (myotonic) Parkinson’s patients can appear increased muscle tone, that is, let the patient in a state of muscle relaxation to his examination, help the patient to do the passive activities of the limbs, will feel like force bending soft lead pipe, also known as “lead pipe-like straightening”; if accompanied by tremor, will feel in the uniform resistance of intermittent pauses, like This is also called “gear-like ankylosis”. Due to the stiffness of the muscles, the patient presents with a specific posture. The muscles of the limbs, torso and neck are stiff, showing the head tilted forward, the body bent down, the elbow joints bent, the wrist joints straightened, the forearms inward, the hip joints and knee joints of the lower limbs slightly bent, and the posture of the hands and feet is also very special, with the interphalangeal joints straightened, the fingers inward, and the thumb to palm, forming a very special posture. 3. Motor retardation Patients can self-control fewer random movements, and have difficulty taking the first step when starting and turning around, and the movement is slower than before. The patient’s writing gradually becomes more difficult and smaller and smaller, which is known as “lowercase syndrome” in medical science. In severe cases, patients are unable to take care of themselves and have difficulty washing their faces and brushing their teeth. When the movement disorder occurs in the facial muscles, the patient is like wearing a mask, called “mask face”: expression is dull, blinking is reduced, and the eyes are staring forward; when it occurs in the mouth, tongue, and pharynx, there is an inability to swallow saliva naturally, resulting in drooling and choking when drinking; when it occurs in the extremities, walking is reduced. 4. Posture and gait disorders Postural instability is an advanced symptom of Parkinson’s disease, mostly occurring 5 years after the appearance of symptoms. Patients have balance disorders and often fall forward because they cannot adjust their posture in time. Gait abnormalities are manifested as difficulty in starting when walking, once started, the body leans forward, the center of gravity shifts forward, the pace is small but faster and faster, and cannot stop in time, called “panic gait”.