(1) If the cause of difficulty sleeping at night in Parkinson’s disease is insomnia (1) first you need to rule out that it is not caused by taking anti-Parkinson’s drugs (such as Slegiline or Amantadine) at night; (2) some other simple methods can help improve sleep, such as ensuring a normal sleep schedule, increasing the amount of daytime activity, resting before bedtime (such as taking a hot bath) avoiding alcohol, tobacco and Caffeine. Insomnia and other sleep disorders are more common in people who are depressed. Therefore, doctors should recommend a treatment plan to deal with depressed mood. 2. If sleep problems are due to increased nighttime symptoms such as stiffness, difficulty turning in bed, pain and tremors, your doctor may consider a longer-acting medication such as once-daily levodopa tablets or a long-acting dopamine agonist. Morning dystonia may require aporphine injections at certain times, usually administered by the patient or a caregiver; long-acting dopamine agonists may also be considered at night. In the case of nocturnal dyskinesia with pain, the patient may need to take some pain medication at night. If it is difficult to turn over while sleeping, use smoother sheets and install bed rails. If the sleep disorder is due to nocturia: (1) The patient should try and make sure to reduce fluid intake at night and go to the bathroom once before going to bed; (2) Avoid drinking beverages such as coffee, tea or beer before going to bed; (3) The patient may need special medications such as oxybutynin or tolterodine. (3) Patients may need special medications such as oxybutynin or tolterodine. These medications can cause the bladder, which has become unusually sensitive due to Parkinson’s medications, to urinate quickly; (4) Have a bedside potty available in case you need it. 4. Less frequently, sleep disturbances are due to restless legs syndrome, which is caused by overproduction of dopamine in the brain or over-excitation of dopamine receptors causing involuntary movements at night: (1) the dose of levodopa needs to be adjusted at night; (2) a long-acting dopamine receptor agonist is needed at night. In some cases, nocturnally acting drugs such as clonazepam or zopiclone may be effective. 5. If the sleep disturbance is due to a neurological problem (e.g., hallucinations) or abnormal behavior at night (e.g., sleepwalking, stirring, talking aloud in sleep), the patient needs to consult with a physician about his or her treatment options.