The side effects of angiography vary according to the patient’s own disease and the examination process, and are divided into the following aspects: 1. puncture: pain at the puncture site, some patients with poor vascular conditions, vascular rupture during puncture, resulting in subcutaneous bleeding or even hematoma formation; 2. contrast agent: adverse reactions can occur after injection of contrast agent into the blood vessels, such as transient headache, generalized numbness, and even colic and spasm; 3. Vasospasm: some patients may experience spasm when injecting contrast medium into the blood vessel, resulting in narrow lumen, so that the contrast medium fails to enter the blood vessel or enters incompletely, resulting in failure of contrast; 4. Cerebral infarction: the contrast medium may lead to the dislodgement of atherosclerotic plaques from the inner wall of the blood vessel, which enters into the cerebral blood vessel leading to cerebral infarction, or even cerebral hemorrhage.