Renal lymphoma is a solid tumor originating from the lymphoid tissue of the kidney. Renal lymphoma is a malignant tumor that originates from lymphoid tissue within the renal envelope or perirenal fat. With the continuous development of the disease, it forms infiltrative invasion of renal organs, which is rare in clinic, mostly secondary to leukemia and disseminated lymphoma, and is accompanied by lymph node enlargement, splenomegaly, renal function impairment and other symptoms. In early stage, the size of renal lymphoma is small, and radical surgery is often adopted for resection, and auxiliary radiotherapy and chemotherapy can be used after surgery. In advanced stage, chemotherapy is mainly used to shrink the tumor lesions, supplemented by surgery and radiotherapy to help prolong the survival cycle and improve the quality of life. It is recommended that patients with renal lymphoma should go to regular hospitals regularly, follow the diagnosis and treatment advice of specialists, standardized treatment and regular follow-up.