Simethicone, generic name is montelukast, after taking whether you can vaccinate need to be specifically analyzed. 1. Simply take montelukast: this drug for the gastrointestinal mucosa has a certain protective effect, generally will not be absorbed by the gastrointestinal mucosa, so there is no direct adverse reaction to the vaccine, this situation can be considered vaccination. 2. Combined with other drugs: If the patient belongs to the acute diarrhea or other acute diseases need to take montelukast, at the same time need to take other antibiotic treatment, this situation is not recommended for vaccination, because of acute diseases vaccination is contraindicated, need to be cured of the acute disease can be vaccinated. Montelukast common adverse reaction is occasionally constipation, if mild constipation occurs during the period of taking, you can reduce the dose of taking. Montelukast is contraindicated in people who are allergic to Montelukast. In addition, the use of Montelukast has certain risks, patients need to get the guidance of a specialist.