Waking up with a bitter, dry and sticky mouth can be caused by a variety of reasons, common oral diseases, gallbladder disease, etc., need to be specifically analyzed. 1. Oral diseases: such as dental caries, gingivitis, etc., can appear dry mouth, bitter and sticky symptoms, usually need to maintain oral hygiene, diligent brushing, rinsing after meals, to avoid more serious oral diseases. 2. Gallbladder diseases: such as cholecystitis, gallbladder stones, etc., this time the patient can also appear in the dry mouth, bitter mouth, sticky symptoms, is due to the poor function of the gallbladder, bile reflux caused by the oral anti-inflammatory cholecystolithiasis tablets for treatment, usually on time to eat breakfast, to avoid the reflux of bile. When the symptoms of bitter mouth, dry throat and sticky, we should go to the hospital in time, to clarify the cause, under the guidance of the doctor to use drugs, avoid self-medication.