Four Rebellious San has the efficacy of dispersing the evil spirits and relieving depression, dredging the liver and regulating the spleen, and is effective in treating the symptoms of yang depression and syncope (cold extremities caused by poor circulation of yang qi), and the symptoms of liver-spleen disharmony (inability of the liver and spleen to harmonize their work). However, there is no such thing as “miraculous effect” in clinical practice. 1. Penetrating evil and relieving depression, used for Yang depression and syncope, with clinical manifestations such as lack of warmth in the hands and feet, abdominal pain, diarrhea and discharges. Yang qi stagnation in the body can not be evacuated, the hands and feet can not get the warmth of yang qi is cold; Yang qi stagnation in the abdomen, abdominal pain, diarrhea and discharges. In Si-Wei San, Chai Hu evacuates yang qi; Paeoniae Alba relieves abdominal pain; Citrus aurantium harmonizes qi; Glycyrrhiza glabra harmonizes all medicines (harmonizes the medicinal properties of different Chinese medicines). 2. To relieve the liver and regulate the spleen, for evidence of disharmony between the liver and the spleen, with clinical manifestations such as distension and discomfort in the hypochondrium and ribs, and pain in the epigastrium (abdomen). When Liver-Qi stagnation (poor transportation of Qi and blood in the liver, emotional depression) is not relieved, there will be distention and discomfort in the ribs; when Liver-Qi offends the spleen, there will be pain in the epigastrium (abdomen). Chai Hu and Citrus aurantium dredge the liver and regulate qi (regulating stagnation of liver qi); Paeonia lactiflora nourishes the blood and softens the liver (tonifying the blood and softening the liver); and Glycyrrhiza glabra harmonizes all the herbs. Adverse effects of Si Reverse San are not clear; prohibited for those who are allergic to this product; caution for allergic individuals; caution for pregnant women; caution for those who suffer from dystocia (pain in the area of the coarseness and ribs) due to deficiency of liver and yin; caution for those who do not have warmth in the limbs due to cold syncope. Avoid cold and greasy food during the medication. If you need to take Si-Rei San, it should be used under the guidance of traditional Chinese medicine practitioners, and individuals should not take the medicine on their own.