If a female patient has black lips, it is usually necessary to consider the following factors: 1, to consider whether the factors of poisoning, such as nitrite poisoning in food poisoning, will lead to black and purple lips. 2, for women if there is obvious anemia or endocrine disorders, premature failure of the ovarian function, there will be black lips. 3, some cardiogenic diseases, such as Coronary heart disease, myocarditis, pericarditis, heart valve disease, or hypertrophic obstructive cardiomyopathy, in which case the coronary arteries will be insufficient blood supply, the patient will also have the symptom of black lips. 4, respiratory diseases, such as chronic bronchitis, chronic bronchodilatation, chronic obstructive pulmonary emphysema, pulmonary heart disease, because of the decline in arterial oxygen saturation will lead to black lips.