Toe crevice rot itch may be suffering from eczema or erosive tinea pedis, need to clarify the cause of the disease and then symptomatic treatment. 1. Eczema: foot eczema can lead to toe crevice erosion with itching, you can use 3% boric acid solution wet compresses or external application of glycerite lotion, while with oral benadryl, cetirizine, fexofenadine and other antihistamine drugs for treatment. 2. Vesiculobullous tinea pedis: can also lead to toe crevice rotten itch, need to use antifungal drug treatment, such as clotrimazole cream, bifonazole spray, miconazole nitrate ointment. In addition to medication, the choice of comfortable and breathable shoes and socks is also particularly critical, you need to develop a good habit of changing shoes and socks, to assist in the treatment. There may be other reasons for itchy toes, so it is recommended to go to the dermatology department of the hospital to get a clear picture of the cause of the problem and follow the doctor’s instructions for symptomatic treatment.