In recent years, the use of ultrasound in regional blocks has become increasingly widespread. The existing literature focuses on ultrasound-guided interosseous groove, supraclavicular, subclavicular, axillary brachial plexus nerve, sciatic nerve, and femoral nerve blocks, and ultrasound-guided lumbar plexus, ventral plexus, and stellate ganglion blocks have also been reported. The use of ultrasound guidance has been shown to significantly reduce the difficulty of neuraxial blocks in adults, children, and pregnant women in labor. Traditional peripheral nerve block techniques do not have visual guidance and rely primarily on somatic anatomical landmarks to localize the nerve, with the risk of block failure due to suboptimal needle tip or injection location; in patients with difficult anatomical localization, repeated punctures and prolonged operation times result in unnecessary pain for the patient and frustration for the operator. The use of ultrasound guidance in regional blocks allows clear visualization of the nerve structures and the vascular, muscular, skeletal, and visceral structures surrounding the nerve; real-time images of the puncture needle’s travel are provided during needle insertion so that the needle direction and depth of insertion can be adjusted at any time while the needle is being inserted to better approach the target structure; drug diffusion can be seen during injection to screen unconscious intravascular injections from unconscious intra-neural injections; in addition, the There is evidence that the use of ultrasound guidance can shorten the onset of sensory block, improve the block success rate, reduce the number of punctures, and decrease nerve injury compared to neurostimulators. The basis of ultrasound-guided regional block technique is the acquisition of ultrasound images and the recognition of tissue structures. Skillful use of ultrasound in daily regional block work requires proficiency in the basic principles of ultrasound imaging and the use of ultrasound instruments, familiarity with the anatomy of the scanning site, and the ability to select appropriate scanning techniques to obtain better ultrasound images, as well as proficiency in needle insertion techniques so that the puncture needle can reach the target structure smoothly.