You can usually drink patchouli after drinking alcohol, but it is not recommended to drink patchouli immediately after drinking alcohol because it also contains 20-30% alcohol. If taken at the same time, it can easily lead to alcohol allergy or alcohol poisoning due to excessive alcohol intake, so it is recommended to take patchouli after drinking for 30 minutes. If you drink patchouli after drinking alcohol, you should never take beta-lactam drugs, usually cephalosporins and penicillins at the same time. If you drink patchouli after drinking alcohol and take beta-lactam drugs at the same time, it can cause a disulfiram-like lethal reaction, which can cause itchy skin and allergies in mild cases, and can lead to anaphylaxis and even threaten life in severe cases.