There is no authoritative information to show how late the second shot of HPV vaccine can be postponed to play, generally after the first shot of HPV vaccine can be postponed to play the second shot of HPV vaccine for 1 month, generally can be 1~2 months after the first shot of HPV vaccine for the second shot of HPV vaccine. HPV vaccine can be categorized into bivalent HPV vaccine, quadrivalent HPV vaccine, nine-valent HPV vaccine and so on. If severe fever occurs when you are preparing for the second HPV vaccination, you need to delay the HPV vaccination appropriately, and generally the second HPV vaccination should not be delayed for more than 1 month. In case of bivalent HPV vaccine, the second bivalent HPV vaccine should be given 1 month after the first bivalent HPV vaccine. In case of Quadrivalent HPV Vaccine or Nine-valent HPV Vaccine, the second dose of Quadrivalent HPV Vaccine, or Nine-valent HPV Vaccine should be given 2 months after the first dose of Quadrivalent HPV Vaccine or Nine-valent HPV Vaccine. It is advisable to consult the local hospital on how long the second HPV vaccination can be delayed, and the doctor will judge the specific delay time according to the woman’s own situation.