The disadvantages of the radio wave knife may be the damage to the body, poor treatment of tumors with multiple or too large foci, and expensive treatment. Radio-wave knife, also known as stereotactic radio-wave surgical platform, is a kind of whole-body stereotactic radiotherapy equipment, which can treat tumors in all parts of the body. 1. Damage to the body; Radio Wave Knife uses radiofrequency waves as energy to cut, excise, hemostasis, ablation, removal or destruction of tissues. Although the accuracy is very high, it still damages the normal tissues, leads to edema of brain tissues, makes hair fall off, and causes side effects such as radioactive pneumonia. 2. Poor therapeutic effect on tumors with multiple or large foci: Generally speaking, the therapeutic effect is relatively poor for tumors with a diameter larger than 4cm and multiple tumors. 3. Expensive cost: radiofrequency knife can only treat one lesion at a time, which is expensive for many times and long time. It is recommended that patients should standardize the treatment under the guidance of professional doctors if they have tumors to avoid adverse effects.