Coughing up yellowish-green sputum is most commonly an inflammatory reaction caused by Pseudomonas aeruginosa infection of the respiratory system, including acute upper respiratory tract infections, bronchitis, and pneumonia. Antibiotics that fight Pseudomonas aeruginosa can be taken, such as aminoglycosides, including gentamicin and tobramycin. Quinolones including ciprofloxacin, levofloxacin, etc., cephalosporins can also choose to take ceftazidime, cefpirome, penicillins can choose piperacillin, ticarcillin, etc., if the inflammation is relatively more serious can also choose to choose two of the different types of antibiotics taken in combination.