Gout uric acid lowering after still feel pain may be a joint within the local inflammation has not yet subsided, the inflammatory response triggered by the pain and discomfort. Gout is a disorder of purine metabolism and/or impaired excretion of uric acid, causing high blood uric acid, resulting in recurrent attacks of arthritis. When blood uric acid is elevated, urate crystals are deposited in the synovial membrane, cartilage and surrounding soft tissues of the joints, triggering a localized inflammatory response and pain and discomfort. When blood uric acid decreases, some patients with acute gout still feel pain or experience increased pain. This is because in the synovium and surrounding soft tissues, there is still a large amount of uric acid or urate deposits, blood uric acid lowering, will cause these uric acid or urate transfer to the blood, again induced or aggravated inflammatory response, triggering pain. For gout patients should avoid fluctuations in blood uric acid concentration. If gout uric acid lowering still feel pain is recommended to timely to the regular hospital to seek medical treatment, follow the doctor’s instructions standardized treatment.