The skin pimples closed mouth, consider and acne related, belong to the follicle sebaceous glands of chronic inflammatory disease, can cooperate with the doctor to give daily care, topical medication, brushing acid treatment and other ways to improve. 1. Daily care: patients should pay attention to local hygiene and cleanliness, you can use mild oil-control cleanser to clean the face, which can effectively remove the residual harmful substances on the face, thus improving the symptoms of acne vulgaris. 2. Topical medication: For patients with a lot of acne, you can work with your doctor to apply topical medication such as Vitamin A cream, Adapalene gel, etc. These medications can play a role in dissolving the effects of acne, and at the same time can play an anti-inflammatory role. 3. Acid brushing treatment: such as fructic acid and salicylic acid, this method can inhibit Propionibacterium acnes and regulate keratin, so as to treat the symptoms of acne vulgaris. If acne is diagnosed as the cause of acne, it is recommended that standardized treatment be carried out as soon as possible in order to reduce the adverse effects of the disease.