2-year-old baby cold vomiting and diarrhea is mostly seen in acute gastroenteritis, treatment needs to strengthen the daily care, oral montelukast and other symptomatic treatment, anti-infection and other causative treatment. Acute gastroenteritis is a common digestive disease in young children, clinical symptoms of vomiting and diarrhea. For such babies, first of all, we need to strengthen the daily care, such as reasonable diet, eat light, easy to digest food, for vomiting serious need to fast for a short period of time. At the same time, oral montelukast to stop diarrhea, oral probiotics such as clostridium casei and other drugs to regulate the intestinal flora, to help alleviate the symptoms of the disease, the course of the disease in dehydration, the need to use oral rehydration salts to increase the intake of water electrolytes, and if necessary, the need for intravenous fluid therapy. Bacterial infection, the need to actively use antibacterial drugs, such as cefixime and other drugs for anti-infection treatment. It is recommended that babies with cold vomiting and diarrhea actively consult a specialist physician to assess the condition and reasonable intervention. All of the above medications should be used under the supervision of a physician.