Black spots on the tip of the tongue may be caused by food residue, or melanoma, oral cancer and other diseases. 1. Food residue: If you have recently eaten food with melanin, some food residue will be left on your tongue, and then black spots will appear on the tip of your tongue. 2. Melanoma: The cause of this disease is still unclear, but the risk factors for melanoma include low melanin, heredity, weakened immune system, improper use of antibiotics, and a history of excessive ultraviolet light exposure. Typical symptoms are pigmented spots on skin and mucous membranes, which may be black, brown or tan in color, and in some cases, it can be manifested as black spots on the tip of tongue. 3. Oral cancer: According to clinical research, the occurrence of this disease is related to smoking, drinking, heredity, nuclear radiation, air pollution, betel quid chewing, viral infection, oral impurity and other factors. The patient’s oral mucosa will appear hard nodules, and with the development of the disease, it will turn into erosion and ulcers, so the black spot on the tip of tongue may be caused by oral cancer. It is recommended that patients with black spots on the tip of the tongue should go to the hospital for a complete and relevant examination to clarify the specific cause.