A transaminase of more than 1000 indicates hepatocellular necrosis and more serious liver function impairment. The normal value of aminotransferase is 0~40 U/L. Generally speaking, if the aminotransferase is elevated more than 2.5 times of the normal value and the abnormality persists for more than half a month, it indicates that the liver cells are damaged obviously. When it exceeds 1000U/L, it suggests serious liver function abnormality. When transaminase exceeds 1000U/L, it may be related to the use of drugs that damage the liver, alcoholic hepatitis, viral hepatitis, etc.; in addition to the liver, other organs and tissues in the body, such as the heart, kidneys, brain, lungs, testes, muscles, etc., contain transaminase, and the transaminase can be abnormally elevated by the suffering from myocarditis, tuberculosis, etc.. It is recommended to consult a doctor in time to identify the cause of the disease and treat it under the guidance of a professional physician, so as not to delay the condition.