Gout in the ankle pain relief commonly used non-steroidal anti-inflammatory drugs, colchicine treatment, if necessary, the use of glucocorticoid combination therapy. 1. Commonly used non-steroidal anti-inflammatory drugs, including indomethacin, diclofenac, etc., can effectively relieve pain symptoms, but should pay attention to its adverse effects, common adverse effects include gastrointestinal ulcers and bleeding, liver and kidney function impairment. Those with a history of peptic ulcer should be prohibited from taking these drugs. 2. Colchicine: Small doses of colchicine in the early stage (within 48 hours) may be effective in relieving symptoms. 3. For patients who cannot tolerate NSAIDs, colchicine, or who are not well treated with the above medications, glucocorticoids (e.g., prednisone) can be given for a short period of time, which may also provide significant symptomatic relief. If gout in the ankle exists, it is recommended to seek medical advice as soon as possible, and take medication under the guidance of a doctor to relieve the uncomfortable symptoms as soon as possible.