Cerebral palsy (CP), as a motor disability, primarily affects the growth and development of children, but also very much affects psychosocial and emotional maturation. Children with CP will be at increased risk of injury and susceptibility to disease, and will have a significant financial burden in terms of health care, rehabilitation and education. The average life expectancy is also significantly shorter. It is a heavy burden for individuals, families and society. Therefore, we should look for solutions to reduce the incidence and severity of CP. The two main concomitant conditions of CP are asphyxia and preterm birth. Prevention of asphyxia and prematurity and their optimal management to reduce brain damage are important to reduce the occurrence of cerebral palsy. Early diagnosis Cerebral palsy is a syndrome caused by non-progressive brain injury during the first month of development, mainly manifesting as central motor deficits and postural abnormalities. It may be accompanied by mental retardation, convulsions, behavioral abnormalities or perceptual disturbances, and requires the exclusion of central paresis due to progressive diseases and transient developmental lags in normal children. Children with cerebral palsy have the following four abnormalities: delayed motor development; abnormal muscle tone and posture; reduced and/or abnormal active movements; and abnormal reflexes. However, the delayed onset of signs of cerebral palsy and the complex nature of development make early diagnosis of cerebral palsy difficult. Children with cerebral palsy are normal and healthy to some extent during the neonatal period. Due to hypertonia of the extensor muscles, the infant may be able to lift the head early in the prone position and hypertonia of the lower extremities. Before 5 to 6 months, this is manifested by standing up with the hip and knee joints extended when pulling the child to a sitting position, while normal children can only be pulled to a sitting position during this period. Cerebral palsy is an abnormality of motor function and a disability. There are no quantitative criteria for motor function abnormalities as cerebral palsy, and there are no early signs, imaging or laboratory tests that can confirm the diagnosis. Cerebral palsy is always a detective diagnosis because the positive evidence is indirect and based only on the behavior and development of a given period. Although cerebral palsy is a non-progressive disorder, it is developmental in nature and must be seen as related to changes in the growing infant, and the dual characteristics of the resting nature of the lesion and the dynamic changes in development should be seen. Motor abnormalities appear later in infancy. It manifests when the neural pathways become functional, as in the case of upper limb palsy that does not manifest until the function of the hand is present. The process of selective neural growth and development allows motor deficits to appear at different rates and sequences. Abnormal motor features appear only when the damaged nervous system matures. For example, evidence of spastic cerebral palsy may not be seen until 7 to 9 months of age. Hypotonia appears after one month in infants with hyperbilirubinemia, normal reflexes are maintained for 1 year, and motor development is delayed until 1 to 2 years of age when there is a gradual change from hypotonia to tonicity, followed by bradykinesia-like movements. Ataxia usually manifests itself after 30 months to 3 years of age. Central nervous system immaturity can lead to agitation, feeding difficulties, and sleep disturbances, and these findings may be related to true motor sensory deficits later in life or may be transient neurological deficits. Because early intervention in cerebral palsy is more effective, diagnosis and initiation of treatment should not wait until the development of spastic feet, dystonic posture, or ataxic gait. It is also important not to diagnose cerebral palsy prematurely without sufficient basis to avoid heavy emotional and material burden on parents. It is necessary to use the developmental method as the basis of diagnosis, which requires pediatricians, maternal and child health workers to have a broad knowledge of physiology and pathology, and to be familiar with the laws of motor and intellectual development of children, in order to recognize the developmental abnormalities as early as possible, and to use appropriate methods to directly and effectively correct the various defects of the nervous system. Developmental diagnosis methods and steps 1. Developmental history: complaints; family and genetic history, such as pregnancy, labor/delivery, perinatal/neonatal; developmental indicators, when smiling, prone head lifting, hand grasping, sitting, crawling and standing; other developmental features, social interaction, self-care and emotion; past history, especially convulsions, headache and behavioral abnormalities; 2. Developmental physical examination: head circumference size, abnormal signs 2. Developmental physical examination: head circumference, abnormal signs, reaction to environment, functional activity of sensory organs and behavioral characteristics. The developmental neurological examination includes general observations and the quality of general movements (GMs), which are of two types: twisting movements from the 9th week of gestation to the 8th week of life, and restless movements from the 6th to 9th week of life to the 20th week of life. There is a high sensitivity and specificity in predicting prognosis at 2 years of age. The sensitivity is 94.5% (from preterm, full term to 3rd month); specificity is low early and gradually increases from full term to 3rd month, reaching 82% to 100%; dystonic motor behavior type includes primitive motor type i.e. primitive reflex; postural motor type i.e. postural reflex; sensory: touch, pain; cranial nerve; cerebellar function; dystonia, motor signs, upper neuron, lower neuron. 4. Developmental screening: such as NBNA, Ameil-Tison and CDCC, etc. 5. Laboratory evaluation: selective blood and urine routine, serum lead, TORCH screening, thyroid function, PKU, urine amino acid screening, CT, MRI, etc., and EEG for those with tamponade. 6. Diagnosis:Developmental delay, when a suspected indicator is found but the diagnosis of cerebral palsy cannot be confirmed, it is best to inform the parents It is best to inform the parents that the child has developmental delay so that the parents can pay attention to it mentally. This initial diagnosis lays the foundation for further management. Parents are advised to come to the clinic regularly so that changes can be monitored and further diagnostic and laboratory tests can be recommended; parents are instructed on how to care for the child with developmental delay; interventions are initiated and parents are instructed on how to promote normal development of the infant’s nervous system and correct and overcome the signs of developmental delay. It is important to emphasize that the diagnosis of cerebral palsy should be confirmed after 1 year of age. However, if there are high-risk factors such as asphyxia and premature birth. There are definite abnormalities of GMs, abnormal muscle tone, delayed disappearance of primitive reflexes and delayed or incomplete appearance of postural movements within 3 to 4 months of age. The diagnosis of possible cerebral palsy can be made early, even before the appearance of obvious signs of cerebral palsy. Using this continuous developmental evaluation step can provide a systematic basis for the diagnosis of cerebral palsy within the first few months of life. As the central nervous system grows and develops, fixed motor lesions of cerebral palsy will inevitably be seen. This is a dynamic process that begins at least immediately at birth, and motor signs can disappear in very mild cases in the early years. Cerebral palsy is only considered when a range of motor developmental deficits are present. The determination of cerebral palsy specific phenotype is also often consistent with age, such as the inability to form a thumb pinch at 9 to 10 months of age, which may be the first sign of hemiplegic upper extremity abnormalities. The diagnosis of the specific type of cerebral palsy and the degree and extent of involvement can only be made when the child is growing.