The relationship between turned-up lips and leukemia is that leukemia can potentially cause patients to experience turned-up lips. Acute leukemia can develop infections in the gums, perianal area, lungs, and at the mouth where symptoms such as gum growth, swelling, or bleeding gums can occur. These causes may then cause the patient to develop lip upturning. In addition, patients with chronic rhinitis, sinusitis, nasal septum distortion, adenoid hypertrophy and other diseases are forced to use the mouth to breathe, and the airflow passes through the upper jaw of the mouth for a long time; there are bad habits such as tongue habitually licking the front teeth, biting hard objects, and sucking the fingertips; and trauma and other factors can also lead to lip turning up. If the lips turn up, it is recommended to go to the hospital to improve the relevant examination to find out the cause of the lips turn up.